Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 0.375


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCA1chrX_-_1286574400.831.1e-02Click!
SMARCC2chr12_-_565832440.733.9e-02Click!
DMAP1chr1_+_446791110.705.1e-02Click!
SMARCA5chr4_+_144434555-0.696.0e-02Click!
NCOR2chr12_-_1250520090.147.5e-01Click!
NCOR1chr17_-_160978820.127.8e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_159175048 0.616 NM_001122951
 DARC
Duffy blood group, chemokine receptor
chr5_+_92918924 0.424 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_-_12973752 0.318 NM_001164271
 DLC1
deleted in liver cancer 1
chr1_-_168698412 0.293 NM_001937
 DPT
dermatopontin
chr8_-_108510094 0.252 NM_001146
NM_001199859
 ANGPT1

angiopoietin 1

chr5_-_19988293 0.237 NM_001167667
NM_004934
 CDH18

cadherin 18, type 2

chr6_+_72596699 0.219 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_71502700 0.211 MAP1B
microtubule-associated protein 1B
chr7_-_92777657 0.211 NM_152703
 SAMD9L
sterile alpha motif domain containing 9-like
chr13_+_24144402 0.211 NM_001204459
NM_148957
 TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr6_+_72596405 0.207 RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_154230157 0.203 C5orf4
chromosome 5 open reading frame 4
chr5_-_154230212 0.194 NM_032385
 C5orf4
chromosome 5 open reading frame 4
chr2_-_188419185 0.193 NM_001032281
NM_006287
 TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr1_+_221052735 0.188 NM_021958
 HLX
H2.0-like homeobox
chr1_+_221052845 0.185 HLX
H2.0-like homeobox
chr16_-_4896197 0.182 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr6_+_72922513 0.180 NM_001168407
NM_001168408
 RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_221053000 0.179 HLX
H2.0-like homeobox
chr6_+_136172802 0.166 NM_018945
 PDE7B
phosphodiesterase 7B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
4.08 2.39e-03 GO:0034340 response to type I interferon
3.89 9.99e-03 GO:0060337 type I interferon-mediated signaling pathway
3.89 9.99e-03 GO:0071357 cellular response to type I interferon
1.75 4.43e-03 GO:0006955 immune response
1.38 5.12e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.37 1.28e-02 GO:0048519 negative regulation of biological process
1.37 1.87e-02 GO:0051252 regulation of RNA metabolic process
1.37 2.36e-02 GO:0006355 regulation of transcription, DNA-dependent
1.37 3.86e-02 GO:0048523 negative regulation of cellular process
1.36 8.19e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.35 3.50e-04 GO:0060255 regulation of macromolecule metabolic process
1.34 1.27e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.34 1.77e-02 GO:0031326 regulation of cellular biosynthetic process
1.34 4.62e-02 GO:0006950 response to stress
1.33 3.94e-04 GO:0080090 regulation of primary metabolic process
1.33 1.70e-02 GO:0009889 regulation of biosynthetic process
1.33 2.60e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 3.56e-02 GO:0010468 regulation of gene expression
1.31 1.31e-03 GO:0031323 regulation of cellular metabolic process
1.28 3.34e-03 GO:0019222 regulation of metabolic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
10.04 2.43e-02 GO:0005132 interferon-alpha/beta receptor binding
2.88 5.20e-04 GO:0003714 transcription corepressor activity
1.73 3.66e-03 GO:0043565 sequence-specific DNA binding
1.68 1.69e-04 GO:0001071 nucleic acid binding transcription factor activity
1.68 1.69e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 4.58e-02 GO:0005515 protein binding
1.08 2.88e-02 GO:0005488 binding